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Update
August 7, 2026 03:41 PM GMT
Biopharma | North America
Morgan Stanley & Co. LLC
Terence C Flynn, Ph.D.
Equity Analyst
A picture is worth a thousand
words
Alexander Yevdokimov, Ph.D.
Research Associate
Chris Yu, J.D., Ph.D.
Equity Analyst
Comprehensive US drug market analysis (IQVIA Rx). The latest
weekly Total Prescription YoY growth (wk ending 7/31) was
+1.5% vs. +2.0% last wk and +1.3% over the past 12 wks.
Hailey Horowitz
Research Associate
Damien H Kerner
Research Associate
For week ended Jul 31, US total market weekly TRx YoY change was +1.5% vs.
+1.9% year ago ( Exhibit10 ). Rolling 4-week TRx YoY was -0.2% and rolling 12-week
Connor M Massari
Equity Analyst
TRx YoY was +1.3%. Extended unit (EUTRx) weekly YoY growth was +1.1%, below
TRx YoY ( Exhibit 13 ). Sequential weekly TRx growth was -0.5% compared to -0.4%
Morgan Stanley India Company Private Limited+
week before. Exhibit17 – Exhibit19 depict YoY momentum for key products.
Saket Agarwal
Research Associate
BMY's Cobenfy was approved for schizophrenia on 9/26/24. Scripts are ~3,370 for
the week vs ~3,290 last week. For full details on our views on the launch, see our
note "Contextualizing Cobenfy launch expectations", where we discuss that the
analogs we are most focused on are the schizophrenia volumes from the Rexulti,
Major Pharmaceuticals
North America
Industry View
In-Line
Caplyta, and Lybalvi launches. We estimated that to achieve 2026 consensus
expectations, Cobenfy TRx needs to track at ~2-5x the volumes from those launches
(see Exhibit 1 ) based on the implied consensus trend, as '26 estimate is $271mn,
which implies ~186K TRx are required to reach consensus estimates (assuming a ~
$1,450 net price, in line with our estimated price in our BMY model). We also show
the Cobenfy launch to date and our estimate of the trajectory to achieve consensus
relative to recent anti-psychotic launches, with TRx combined across all indications,
in Exhibit 2 below for reference as well.
GILD's Yeztugo vs. Descovy vs. Apretude launch comparison chart ( Exhibit 4 ).
GILD's Yeztugo (lenacapavir) was approved on 6/18/2025.…
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