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Global Pharmaceuticals "US Pharma Rebates: 2026 Commercial insights" Weston
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Global Pharmaceuticals "US Pharma Rebates: 2026 Commercial insights" Weston
a period of
Analyst
growth. However this reflects mix due to generic entries, rather than underlying dina.elmonshed@ubs.com
PBM rebate dynamics (key on-market drugs actually show increasing rebates). +1-212-649 8276
GTN in Obesity is trending higher following 2026 net price cuts.
Xian Deng, PhD, CFA
We see a correlation between higher portfolio uniqueness and lower Analyst
rebates. We define a drug as unique if there is a maximum of one other xian.deng@ubs.com
competing product with similar mode of action. Leveraging our UBS Pharma +44-20-7901 6285
Values database we see improving uniqueness for AZN / BAY / BMY / JNJ / MRK, Nusrat Hossain
which we believe positions these companies well to defend against rebate Associate Analyst
pressure. We see falling uniqueness for NOVO, LLY, and to a lesser extent GSK. nusrat.hossain@ubs.com
+44-20-7883 1586
Therapy area mix shift can also provide insights on future rebate
pressures. We map current & future therapy area mix to see if portfolios are
shifting to higher/lower rebate areas. Mix shift appears to favour JNJ / BMY /
NOVN / PFE / AZN, vs potential future higher rebates for ROG / LLY.
Rebate walls may continue to benefit select companies. At scale, access-
driven rebates favour large incumbents by raising the cost to payers of switching
share to new entrants. Bundling across drugs within a therapy area supports share
defence and follow-on launch access. We see ABBV / BMY / JNJ / SAN as
beneficiaries, while BAY / UCB may face headwinds from competitor rebate walls.
PBMs: Upcoming sector patent cliff and reforms add uncertainty. The sector
faces a meaningful patent cliff in the early 2030s. This likely reduces PBM rebate
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