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Opakalm epilepsy data expected in 2H26
研报英文原文证据摘录
Not for redistribution without written consent of Morgan Stanley
M
Idea
August 11, 2026 11:48 AM GMT
Morgan Stanley & Co. LLC
Biohaven Ltd | North America
Terence C Flynn, Ph.D.
Equity Analyst
Opakalim epilepsy data
expected in 2H26
Alexander Yevdokimov, Ph.D.
Research Associate
Damien H Kerner
Research Associate
What’s Changed
Biohaven Ltd (BHVN.N)
From
To
Price Target
$18.00
$19.00
Hailey Horowitz
Research Associate
Chris Yu, J.D., Ph.D.
Equity Analyst
AlphaSignals Earnings Reaction
Unchanged
In-line
Largely unchanged
Impact to our thesis
Financial results versus consensus
Direction of next 12-month
consensus EPS
Source: Company data, Morgan Stanley Research
Connor M Massari
Equity Analyst
Morgan Stanley India Company Private Limited+
Saket Agarwal
Key pipeline programs remain on track, with Opakalim Ph2/3
focal epilepsy data expected in 2H and BHV-1300 (IgG MoDE
degrader) now in Ph3. We update our model for 2Q results and
trends; we reiterate our OW rating, and our PT goes to $19.
Key pipeline programs remain on track across immunology, neurology, and
obesity/oncology.
(1) Opakalim (BHV-7000; Kv7 activator): BHVN reiterated that topline results from
Research Associate
Biohaven Ltd (BHVN.N, BHVN UN)
Biotechnology | United States of America
Stock Rating
Industry View
Price target
Shr price, close (Aug 10, 2026)
Mkt cap, curr (mm)
52-Week Range
Overweight
Attractive
$19.00
$14.54
$2,196
$18.53-7.49
the Ph2/3 RISE3 trial in focal epilepsy remain on track for 2H26, the first of two
Fiscal Year Ending
12/25 12/26e 12/27e 12/28e
registration-directed studies and, in our view, the key near-term catalyst for the
EPS ($)**
Prior EPS ($)**
P/E
EPS ($)§
Div yld (%)
(6.87)
NM
(6.66)
stock. Recall, in focal epilepsy OLE, opakalim achieved a ≥50% responder rate of
54% comparable to Xenon Pharmaceuticals’ (not covered) azetukalner (AZK; Kv7
potassium-channel activator) data, while maintaining lower rates of dizziness,
somnolence, fatigue, and memory impairment, though cross-trial comparisons are a
key caveat, and we await more definitive pivotal data. We forecast risk-adjusted
2035 opakalim sales of $267mn, which assumes a 40% probability of success (POS)
…
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