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Teva Pharmaceuticals: Ph1b vitiligo data bolsters mid-stage pipeline, helps de-risk 2030+ growth
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Teva Pharmaceuticals: Ph1b vitiligo data bolsters mid-stage pipeline, helps de-risk 2030+ growth
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Teva Pharmaceuticals
Ph1b vitiligo data bolsters mid-stage
pipeline, helps de-risk 2030+ growth
Maintain Rating: BUY | PO: 40.00 USD | Price: 34.57 USD
Vitiligo data establish POC; bolster 2030 tail outlook 07 July 2026
This morning, TEVA provided Ph1b topline for its IL-15 antibody (TEV-‘408) for Equity
treatment of vitiligo – an initial proof-of-concept but small study size limits
Jason M. Gerberry
conclusiveness. TEVA had been framing the efficacy benchmark as advanced-stage Research Analyst
systemic therapies (ABBV’s reg-stage Rinvoq), thus no surprise ‘408 showed efficacy in BofAS jason.gerberry@bofa.com
the ballpark on key facial VASI-75 measure (21% vs. 14-19% Rinvoq; the trial was open
Melanie Fong
label). Per TEVA, its IL-15 was well tolerated with no emerging safety concerns, but Research Analyst
presentation lacked detailed AE table. Commercially, Ph1b support competitive profile BofAS melanie.fong@bofa.com
(efficacy), convenient quarterly dosing and (superficially) no safety red flags. Next, TEVA
Chi M. Fong
plans to conduct a Ph2b dose-ranging study and continues to point to a 2031E time-to- Research Analyst
BLA (if all goes to plan) and present detailed Ph1b at future med meeting (dose-level BofASchi.fong@bofa.com
and detailed AE’s offered). On the CC, most of the questions were around a) Dina Ramadane
representativeness of Ph1b study population vs. typical Ph3, b) dosing considerations. Research Analyst
We reiterate our Buy rating, on re-rate to more durable brand growth profile; we await BofASdina.ramadane@bofa.com
randomized Ph2b data before explicitly adding to our model. Richard Wagner >>
Research Analyst
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