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BSX: Mirus Investment Could Shake Up TAVR Market; Will Third Time Be a Charm?
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BSX: Mirus Investment Could Shake Up TAVR Market; Will Third Time Be a Charm?
Equity Research
Company Update — May 18, 2026
Med Tech - Cardiovascular
Boston Scientific Corporation
Mirus Investment Could Shake Up TAVR Market; Will Third Overweight
Time Be a Charm? Price Target: $75.00
Our Call Ticker BSX
Upside/(Downside) to Target 36.5%
BSX’s investment in Mirus could have significant impact on TAVR market: (1) signals
further shift to balloon expandable valves; (2) implied valuation of $4.5B supports Price (05/18/2026) $54.94
valuation of Anteris; (3) puts pressure on EW to develop X4. Watch Meril/MyVal. 52 Week Range $52.52 - 109.50
Market Cap (MM) $82,135
What happened? BSX announced it has invested $1.5B for a 34% equity stake in MiRus, Enterprise Value (MM) $92,467
a privately held company developing the Siegel TAVR system. As part of the investment, Average Daily Value (MM) $885
BSX also received an exclusive option to acquire the MiRus TAVR system, subject to Dividend Yield 0.0%
additional payments and the completion of certain milestones, for an add'l $3B plus add'l
payments (we assume royalties) based on net sales of the Siegel valve over a specified $ (Dec) Q1 Q2 Q3 Q4 FY
period of time. EPS
2026E 0.80 A 0.83 E 0.85 E 0.90 E 3.37 E
What is Siegel? The Siegel valve is a balloon expandable (like EW’s Sapien 3) built on a 2027E 0.88 E 0.93 E 0.93 E 0.98 E 3.73 E
proprietary rhenium alloy and is the first nickel-free, balloon-expandable TAVR valve. The
Source: Company Data, Wells Fargo Securities estimates, and Factset.
Siegel valve is designed with leaflets made of dry porcine tissue and a nitric oxide-coated NA = Not Available, NC = No Change, NE = No Estimate
rhenium frame, which has a radial strength greater than cobalt or titanium. The open cell
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