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US Biopharmaceuticals: Vegas Healthcare Conference Takes for INSM, LGND, and EIKN
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US Biopharmaceuticals: Vegas Healthcare Conference Takes for INSM, LGND, and EIKN
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US Biopharmaceuticals
Vegas Healthcare Conference Takes for
INSM, LGND, and EIKN
Industry Overview
INSM: Concerns overdone, launch very much on track 13 May 2026
Insmed CEO Will Lewis continued to emphasize the strength of Brinsupri’s launch at our Equity
fireside chat (see our INSM investor dinner takes). Easily overlooked, we think, the early United States
trajectory positions Brinsupri among the top 25 biopharma launches of all time, Biopharmaceuticals
underscoring the magnitude of unmet need in NCFB and the degree to which the current Jason Zemansky
debate remains overly focused on durability. While management did not revisit launch Research Analyst
metrics, it reiterated discontinuation rates remain favorable vs. relevant comps, with BofAS+1 646 855 4280
patient loss addressable as prescriber experience builds and support improves. Perhaps jason.zemansky@bofa.com
more importantly, the market itself continues to expand, with prevalence “stacking” Jacqueline Plesset
Research Analyst
given the chronic nature of NCFB. Insmed also noted Symphony TRx continued to track BofAS
well with its internal prescription data through April, providing another external, positive +1 646 855 0014
jacqueline.plesset@bofa.com
check on the launch trajectory. Beyond Brinsupri, we think TPIP’s upside remains
underappreciated, with ~25% of patients in the phase 2 OLE up-titrating above 640ug,
creating potential for incremental efficacy upside. Ultimately, with shares, in our view,
still trading absent much credit for the commercial/late-stage pipeline opportunities,
we’d argue current levels remain an attractive entry point. Maintain Buy and $214 PO. Abbreviations:
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