GLOBAL RESEARCH ARCHIVE
Q-dub Hunting For Laggards. MLTX CRNX SRPT IVA in re-rate basket. VRDN VERA need to beat launch
Research evidence excerpt
Q-dub Hunting For Laggards. MLTX CRNX SRPT IVA in re-rate basket. VRDN VERA need to beat launch
Biotechnology - Immunology
Cardiometabolic
Genetic Medicines - Market Weight
Immunology - Market Overweight
Q-dub Hunting For Laggards. MLTX CRNX SRPT IVA in July 5, 2026
re-rate basket. VRDN VERA need to beat launch
The Wolfe Byte
The massive biotech rally has prompted investors to track down the biggest laggards and winnards. MLTX CRNX
SRPT IVA are our favorite laggards. Should random profit-taking persist, ZBIO KYMR ORKA SYRE are at risk.
Separately, model updates to BBIO MDGL INSM
With XBI +24% in the last month, recent buyside conversation suggests that investors are hunting for the laggards
and winnards. We believe valuation arguments should become credible for companies that are post-phase 3 (with
consensus on label expectations) and absent of gating catalysts. The APGE deal (our M&A report) cast a positive halo
on a select group of stocks, especially the 'pipeline-in-a-drug I&I basket' (our sector report), but several were left out of
the fun. We argue that the recent laggards SRPT CRNX MLTX can simply trade up on valuation whereas VERA & VRDN
must beat launch expectations. 'Super winnards' (L1M return ZBIO +60%, KYMR +58%, ORKA +51%, SYRE +24%) are
at risk of random profit-taking, which may explain arbitrary single-day weakness recently (ORKA -10%, DNTH -7%,
SYRE -4%).
Laggards that can easily re-rate due to valuation alone
MLTX (OP) has been extremely unresponsive to the biotech rally. L1M idio return -12%. TEEN data positions Moonlake
to capture patients ahead of some competition and the potential label could enable 'best-in-class' status. While we
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